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L’université Paris-Saclay voit officiellement le jour le 5 novembre 2019

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GQE – Le Moulon (Quantitative Genetics and Evolution – Le Moulon)

UMR (Joint Research Unit) AgroParisTech, CNRS, Inra, Université Paris-Sud

General scientific orientation

The Quantitative Genetics and Evolution-Le Moulon (GQE-Le Moulon) joint research unit focuses principally on studies of the genetics and evolution of characters with a complex determinism (quantitative characters). Its major objectives are :
♦ To generate knowledge concerning fundamental multifactorial genetics for the modeling of quantitative variation and its evolution in different populations, and for research on quantitative trait loci (QTLs) ;
♦ To understand the genetic, epigenetic and molecular control of qualitative and quantitative traits, their importance in the evolutionary history of species and their adaptations ;
♦ To guide and optimize approaches for the selection of target traits (growth, development, adaptation), by integrating advances from genomics, valorizing genetic resources and taking into account changes in environmental conditions and cropping methods.
The study models of the GQE-Le Moulon unit depend on the questions posed and the experimental tools available to resolve them. They include species of agronomic interest (wheat, maize and rapeseed), model species (Arabidopsis, yeast) and non-model species (Nigella).

Fields of research

The unit is composed of seven research teams and four transverse teams :
RESEARCH TEAMS
Biology and adaptation of evolving systems (BASE)
♦ Modeling of quantitative variation and its evolution, at the genetic, molecular, genomic, metabolic and environmental levels

Recombination of alleles during meiosis : determinism, applications and modeling (RAMDAM)
♦ Theoretical and experimental studies of the formation of meiotic crossovers
♦ Integrative biology and modeling

Structure and evolution of fungal chromosomes (SECF)
♦ Study of the modes of reproduction of hemiascomycete yeasts, role in the evolutionary history of Candida glabrata
♦ Population genomics, comparative and functional genomics, and adaptation of yeasts to their environment

Genome dynamics and adaptation of crop plants (DyGAP)
♦ Population genomics, comparative and functional genomics, and adaptation of yeasts to their environment

Genetics, epigenetics and evolution of floral morphogenesis (GE2MorF)
♦ Mechanisms underlying the morphological diversity of petals and perianth symmetry
♦ Role of perianth diversity in adaptation and species diversification

Diversity, evolution and adaptation of populations (DEAP)
♦ Study of the genetic basis of local adaptation ; dynamic management of crop-plant biodiversity and its value for innovative sustainable agroecosystems : participatory selection

Quantitative genetics and selection methodology (GQMS)
♦ Study of the genetic basis of complex traits and of the mechanisms of response to selection, optimization of the management of genetic resources and selection processes

TRANSVERSE TEAMS
Mapping, expression and polymorphism workshop
♦ Shared projects in molecular biology, technological scouting and methodology development for specific projects

Bioinformatics and computing workshop
♦ Analysis of genome sequences, development of database programmes for genetics, systems and network computing

Experimental installation
♦ Genetic experimentation in the field, agronomic trials (principally for wheat and maize) and housing of teaching experiments for Université Paris-Sud and AgroParisTech

PAPPSO proteomics platform (IBiSA)
♦ Identification and quantification of proteins, analysis of posttranslational modifications, methodology development, bioinformatics for proteomics

For more information
Publications
Check out the open access publications of GQE-Le Moulon on HAL-AgroParisTech :
https://bit.ly/2OspGnH
and
https://bit.ly/2TDxp3e

Contact details
direction.gqe chez inra.fr
www.moulon.inra.fr
+ 33 (0)1 69 33 23 30

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F-75231 Paris Cedex 05
Tel: 33 (0) 1 44 08 18 43
Fax: 33 (0) 1 44 08 16 00
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